Inter-relationship between rheumatoid arthritis and periodontitis

Several limitations should be acknowledged in our study. First, a case-control design conducted in a hospital setting may introduce selection bias. The admission rate for the target disease could be influenced by the presence or absence of the studied exposure factors. Second, information bias is unavoidable and causality cannot be established. Third, we did not exclude diabetic patients from our study, which might introduce potential confounding bias since diabetes can impact both RA and PD. 

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